CBSE · Class 12 · Biology · Chapter 4

Principles of Inheritance and Variation

Mendelian genetics and inheritance.

12 lessons 215 min
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Lessons in this chapter

  1. 1Foundations of Heredity and Mendel's ExperimentsHow true-breeding pea lines and controlled crosses revealed particulate inheritance.
  2. 2Monohybrid Crosses, Dominance and SegregationAlleles, genotype and phenotype, F1 and F2 predictions, Punnett squares and test crosses.
  3. 3Incomplete Dominance, Codominance and ABO Blood GroupsWhy heterozygotes can show intermediate or simultaneous trait expression, and how ABO alleles interact.
  4. 4Dihybrid Crosses and Independent AssortmentPredicting combined inheritance of two characters and establishing when 9:3:3:1 applies.
  5. 5Chromosomal Theory of InheritanceConnecting Mendelian factors with homologous chromosomes, meiosis and independent orientation.
  6. 6Linkage, Recombination and Genetic MappingHow linked loci produce excess parental combinations and how recombination frequencies estimate genetic distances.
  7. 7Polygenic Inheritance and PleiotropyMultiple genes influencing one trait and one gene influencing multiple phenotypes.
  8. 8Chromosomal and Haplodiploid Sex DeterminationChromosomal sex-determining systems in insects, mammals, birds and honeybees.
  9. 9Mutation and Pedigree AnalysisDNA mutation categories and evidence-based interpretation of human inheritance.
  10. 10Single-Gene Genetic DisordersCausal mechanisms for sex-linked disorders, inherited anaemias and metabolic conditions.
  11. 11Chromosomal Disorders and KaryotypesNumerical chromosome changes, nondisjunction, trisomy 21 and sex-chromosome differences.
  12. 12Chapter Summary and PracticeSynthesis of inheritance mechanisms, chromosome behaviour, human genetics and fully worked chapter-wide problems.